| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
|
|
タイトル |
Frequent Detection of Y Chromosome Sequences in Japanese Turner's Syndrome by Southern Blot Analysis of Amplified DNA |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Turner syndrome, |
| キーワード |
|
|
主題 |
Y chromosome, |
| キーワード |
|
|
主題 |
PCR, |
| キーワード |
|
|
主題 |
Southern blot |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Nakagawa, Yuichi
Natsume, Hiromune
Kubota, Akira
Takeuchi, Hiromi
Nasuda, Kaoru
Toya, Kazuhiko
Endou, Akira
Saegusa, Hirokazu
Takeuchi, Rika
Ogawa, Haruo
Igarashi, Yoshio
|
| 書誌情報 |
Clinical Pediatric Endocrinology
巻 5,
号 2,
p. 83-87,
発行日 1996
|
| 出版者 |
|
|
出版者 |
日本小児内分泌学会 |
| 権利 |
|
|
権利情報 |
The Japanese Society for Pediatric Endocrinology |
| 権利 |
|
|
権利情報 |
本文データは学協会の許諾に基づきJournal Archiveから複製したものである |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
In Turner's syndrome, the detection of Y chromosome sequences is very important because the presence of the Y chromosome increases the risk of gonadoblastoma induction. Some recent studies have indicated the presence of the Y chromosome in patients with Turner's syndrome, by methods in which the Y chromosome was not detected by a standard cytogenetic method, but these studies concentrated on a part of the Y chromosome or used an insensitive methods. In this study, we approached the detection of Y chromosome sequences by a sensitive method, polymerase chain reaction (PCR) with seven pairs of primers that span the Y chromosome, followed by Southern blot analysis, in eleven Japanese patients with Turner's syndrome. Ten of the eleven patients had some Y chromosome sequences determined by PCR followed by Southern blot. This suggests that most patients with Turner's syndrome have cryptic Y chromosomes, but further studies and long-term follow-up of patients with the Y chromosome are needed to support our data and to clarify the significance of a small amount of Y chromosome. |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
09185739 |
| EISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13477358 |
| 出版社DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1297/cpe.5.83 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
Clinical P-5-83.pdf (1.9 MB)
