| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2015-11-20 |
| タイトル |
|
|
タイトル |
Simultaneous determination of coinage metals, copper, silver and gold in tissues using electrospray ionization tandem mass spectrometry |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Copper |
| キーワード |
|
|
主題 |
Silver |
| キーワード |
|
|
主題 |
Gold |
| キーワード |
|
|
主題 |
Electrospray ionization |
| キーワード |
|
|
主題 |
Tandem mass spectrometry |
| キーワード |
|
|
主題 |
Diethyldithiocarbamate |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Minakata, Kayoko
Yamagishi, Itaru
Nozawa, Hideki
Gonmori, Kunio
Hasegawa, Koutaro
Suzuki, Masako
Horio, Fumihiko
Watanabe, Kanako
Suzuki, Osamu
|
| 書誌情報 |
Forensic Toxicology
巻 30,
号 2,
p. 149-155,
発行日 2012-07
|
| 出版者 |
|
|
出版者 |
Springer Japan |
| 権利 |
|
|
権利情報 |
The final publication is available at Springer via http://dx.doi.org/10.1007/s11419-012-0134-9. |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
A rapid and sensitive mass spectrometric method was developed for the simultaneous determination of coinage metals such as copper (Cu), silver (Ag) and gold (Au). The metals in a wet ashed tissue solution were complexed with diethyldithiocarbamate (DDC; C4H10NCS2) and were extracted together with isoamyl alcohol. After the acidification of the extract with oxalic acid, metals were quantified using their product ions, Cu(DDCH)+, Ag(DDCH) + and Au(DDCH)+ that derived from the precursor ions Cu(DDC)2+, Ag(DDC)2 + and Au(DDC)2+, respectively, by electrospray ionization tandem mass spectrometry. The limits of detection were 0.6, 0.3 and 1 μgl?1 for Cu, Ag and Au and the quantification ranges were 2 ? 100, 1 ? 100 and 3 ? 100 μgl?1 for Cu, Ag and Au, respectively. Cu levels in spontaneously hypertensive osteogenic disorder rats at 6 weeks old and at 30 weeks old were found to be 1.8 times and 5.1 times those of the normotensive osteogenic disorder rats, respectively, when using wet-ashed kidney solutions diluted to 1,000 fold. |
| 出版社DOI |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1007/s11419-012-0134-9 |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
ft-30-149.pdf (7.2 MB)
