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Pitfalls in the assessment of gestational transient thyrotoxicosis
http://hdl.handle.net/10271/00003749
http://hdl.handle.net/10271/000037498dcfbc81-1045-4b0c-a071-52644537e56e
| 名前 / ファイル | ライセンス | アクション |
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Gynecol Endocrinol-36-662.pdf (375.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2021-04-26 | |||||||
| タイトル | ||||||||
| タイトル | Pitfalls in the assessment of gestational transient thyrotoxicosis | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題 | Gestational transient thyrotoxicosis | |||||||
| キーワード | ||||||||
| 主題 | Graves' disease | |||||||
| キーワード | ||||||||
| 主題 | human chorionic gonadotropin | |||||||
| キーワード | ||||||||
| 主題 | pregnancy | |||||||
| キーワード | ||||||||
| 主題 | thyroid-stimulating hormone receptor antibody | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
Iijima, Shigeo
× Iijima, Shigeo
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| 書誌情報 |
Gynecological endocrinology 巻 36, 号 8, p. 662-667, 発行日 2020-08 |
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| 出版者 | ||||||||
| 出版者 | Taylor & Francis | |||||||
| 権利 | ||||||||
| 権利情報 | This is an Accepted Manuscript of an article published by Taylor & Francis in Gynecological Endocrinology on 17/04/2020, available online: http://www.tandfonline.com/10.1080/09513590.2020.1754391. | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Gestational transient thyrotoxicosis (GTT) is associated with direct stimulation of the maternal thyroid gland by human chorionic gonadotropin (hCG). It is characterized by slightly higher thyroid hormone and lower thyroid-stimulating hormone (TSH) levels in early pregnancy and mild or no symptoms. While GTT must be distinguished from Graves’ disease (GD), which is associated with maternal and fetal complications, treated GD and new-onset GD in pregnancy are occasionally challenging to distinguish. Evaluating serum hCG levels and TSH receptor antibody (TRAb) titers can help, but the results are not irrefutable due to pregnancy-related immunosuppression. Moreover, GTT can follow unusual clinical courses in relation to some pregnancy complications. Excessive hCG production can cause severe GTT symptoms in patients with hyperemesis gravidarum, trophoblastic disease, or multiple pregnancies. Thyrotoxicosis can emerge beyond the second trimester in patients with gestational diabetes mellitus and mirror syndrome, because of delayed elevations in the hCG levels. Detailed knowledge about GTT is necessary for correct diagnoses and its appropriate management. This review focuses on the diagnosis of GTT, and, particularly, its differentiation from GD, and unusual clinical conditions associated with GTT that require comprehensive management. | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0951-3590 | |||||||
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| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 1473-0766 | |||||||
| PubMed番号 | ||||||||
| 関連タイプ | isVersionOf | |||||||
| 識別子タイプ | PMID | |||||||
| 関連識別子 | 32301638 | |||||||
| 出版社DOI | ||||||||
| 関連タイプ | isVersionOf | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | 10.1080/09513590.2020.1754391 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | AM | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||
